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System Biosciences


System Biosciences,简称SBI,美国加州湾区新成立的生技公司,致力于独特、创新生物技术之开发,以研发利于基因及蛋白质功能鉴定、研究之崭新方法和工具为宗旨

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。 现阶段研发重心为RNA干扰(RNAi)研究之相关工具yabo300。System Biosciences (SBI) 致力于开发独特、革新的技术,为客户研究蛋白组学和基因组学功能提供研究工具yabo300手机端。SBI 是专业的慢病毒产品公司,提供基于慢病毒.


System Biosciences (SBI) develops innovative research tools for Vector delivery technologies, MicroRNA research, Exosome research, and Genome Engineering tools, including the CRISPR-Cas9 SmartNuclease system and PrecisionX HR targeting vectors. 


Highlights: 

Vector Technologies: 

Powerful lentivector systems 

One-step transfection piggyBac transposons 

Single-copy gene additions with phiC31 integrase vectors 

Sustained expression without integration with Minicircle DNA plasmids 

Exosome Research Tools: 

Isolate exosomes with ExoQuick and ExoQuick-TC 

Exo-Flow- Immunopurify exosomes on magentic beads and anlayze by FACS 

Culture cells in exosome-depleted FBS

  Verify exosome recovery with antibodies 

Quantitate exosomes with ELISAs 

Genome Engineering: 

RNA-guided Cas9 SmartNuclease system 

Fast and efficient mutation correction / gene editing 

HR donor vectors for knock-in, knock-out & tagging 

High-throughput, targeted integration with PinPoint technology 

Stem Cell Research: 

iPSC reprogramming systems 

Growth factors and media 

Pluripotency confirmation kits and antibodies 

iPS celllines, normal and disease models 

Promoter lineage reporters in lentivectors 

Non-coding RNA: 

LncRNA qPCR profiling kits 

miRNome and OncoMir qPCR profiling systems 

Lenti-miR Precursor clone libraries – arrayed and pooled 

miRZip anti-miR clones for stable miRNA inhibition Exo-NGS 

Custom Service: 

Provide serum, tissue culture media, or other patient biofluids to SBI 

SBI isolates exosomes, purifies RNA and generates high quality NGS libraries 

Sequencing performed using Illumina MiSeq and HiSeq platforms 

Comprehensive data analysis, including generation of heat maps and top hits, provided 

NGS data loaded onto a custom UCSC Genome Browser for convenient viewing.


产品列表:


Lentiviral Technology

  • Expression Vectors
  • Cumate Inducible Vectors
  • Transcription Reporter Vectors
  • Virus Production
  • Reporter Cell Lines

Genome Engineering

  • EZ-TAL Assembly Kit
  • Cas9 SmartNuclease
  • HR Donor Vectors
  • phiC31 Integrase System
  • PinPoint Targeting System
  • PiggyBac Transposon

Molecular Tools

  • Cold Fusion cloning
  • MetaMorph Mutagenesis Kit
  • mRNAExpress RNA Synthesis Kit
  • PureFection transfection
  • Retrovirus concentration
  • Cyto-Tracers
  • Molecular Imaging Vectors
  • MycoQuick

Minicircle Technology

Stem Cell Research

  • Growth Factors and Media
  • iPSC Reprogramming Systems
  • Antibody and AP Staining Kits
  • iPS Cell Lines
  • Pluripotency Reporters
  • Transdifferentiation Factors
  • Differentiation Reporters

MicroRNA Research

  • Expression Profiling
  • MicroRNA Overexpression
  • MicroRNA Knockdown
  • MicroRNA Virus Libraries
  • Target Selection System
  • Discovery & Cloning

Exosome Research

  • Exosome Isolation
  • Exosome FACS
  • Exosome-depleted FBS
  • Exosome Detection
  • Serum microRNAs

LncRNA Research

RNAi Libraries

  • Application Overview
  • Human Genome-wide
  • Mouse Genome-wide
  • Pathway Focused

Gene Analysis

  • RNA-Quant cDNA Synthesis
  • FullSpectrum
  • MultiStart Primers
  • Interferon Response Detection Kit

Immunology Research

  • Foxp3 vectors
  • RORyt vectors
  • T cell Reporters

 


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